4-METHOXYPHENYL CHLOROTHIOFORMATE(4-METHOXYPHENYL CHLOROTHIOFORMATE) is an organic compound. It has a chemical formula of C8H7ClOS and a molecular weight of 182.65g/mol.
Nature:
-Appearance: Colorless to light yellow liquid
-Solubility: Soluble in organic solvents such as ether and chloroform
-Melting point: about -15 ℃
-Boiling point: about 90-95 ℃
-Density: about 1.27g/cm³
Use:
4-METHOXYPHENYL CHLOROTHIOFORMATE is a carrier reagent commonly used in organic synthesis. It is often used in organic synthesis to synthesize compounds with a thiochloroformate group, and has a catalytic or protective effect. It is widely used in drug synthesis, pesticide synthesis and other organic synthesis fields.
Preparation Method:
4-METHOXYPHENYL CHLOROTHIOFORMATE can be obtained by reacting benzyl alcohol with a thiochloroformate. The specific synthesis method is as follows:
1. Dissolve benzyl alcohol in dry dichloromethane;
2. Add tetraethylamine and cool the reaction mixture to 0°C;
3. slowly add the thiochloroformate to the cooled reaction mixture;
4. The reaction was stirred for 5 hours and the reaction mixture was allowed to warm to room temperature;
5. The product was filtered, washed with ether, and distilled to obtain the pure product.
Safety Information:
4-METHOXYPHENYL CHLOROTHIOFORMATE is an organic compound, so the following safety precautions should be paid attention to during use:
-It may be irritating to the eyes, skin and respiratory tract, and protective equipment should be worn;
-Avoid contact with strong oxidants and strong bases to avoid dangerous reactions;
-Use in a well-ventilated place and away from fire;
-Store in a cool, dry place, avoid direct sunlight;
-If exposed or inhaled, seek medical attention promptly.
When using or handling 4-METHOXYPHENYL CHLOROTHIOFORMATE, be sure to comply with local regulations and safety guidelines.